Dichloromethane → Methanesulfonic acid 3-[1-(3,5-diethoxy-4-fluoro-benzyl)-piperidin-4-ylcarbamoyl]-5-methoxy-phenyl ester
Reaction equation
[CH2:1]([CH3:2])[O:3][c:4]1[cH:5][c:6]([CH2:7][N:8]2[CH2:9][CH2:10][CH:11]([NH:14][C:15]([c:16]3[cH:17][c:18]([OH:24])[cH:19][c:20]([O:22][CH3:23])[cH:21]3)=[O:25])[CH2:12][CH2:13]2)[cH:26][c:27]([O:30][CH2:31][CH3:32])[c:28]1[F:29].[CH2:38]([N:39]([CH:40]([CH3:41])[CH3:42])[CH:43]([CH3:44])[CH3:45])[CH3:46].[CH3:33][S:34]([Cl:35])(=[O:36])=[O:37].[Cl:47][CH2:48][Cl:49]>>[CH2:1]([CH3:2])[O:3][c:4]1[cH:5][c:6]([CH2:7][N:8]2[CH2:9][CH2:10][CH:11]([NH:14][C:15]([c:16]3[cH:17][c:18]([O:24][S:34]([CH3:33])(=[O:36])=[O:37])[cH:19][c:20]([O:22][CH3:23])[cH:21]3)=[O:25])[CH2:12][CH2:13]2)[cH:26][c:27]([O:30][CH2:31][CH3:32])[c:28]1[F:29]Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-2a952017686d499b815463961977d46d
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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