Hydrochloric Acid → HCID 68542631, compound

Participants

Reaction Steps

Dissolve 4-[4-(3-{4-[3-(5-tert-Butyl-isoxazol-3-yl)-ureido]-3-fluoro-phenyl}-imidazo[1,2-a]pyridin-7-yl)-benzoyl]-piperazine-1-carboxylic acid tert-butyl ester (1.53 g, 2.24 mmol) in CH2Cl2 (25 mL), to which is added HCl (5.6 mL, 4 M in dioxane). Stir at room temperature for three hours, then concentrate in vacuo to give light brown solid as product (1.60 g, 115%). MS (ES), m/z 582 (M+1, free base).

Provenance & Evidence