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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1446775Generated: October 31, 2026

2,5-Difluoronitrobenzene → 2,5-Difluoroaniline

https://huagongshe.com/reaction/1446775

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,5-DifluoronitrobenzeneHCID 67767—
ReactantHCID 178418361HCID 178418361—
CatalystNickelHCID 935—
SolventTetrahydrofuranHCID 8028—
Product2,5-DifluoroanilineHCID 67775—

Reaction Steps

A solution of 2,5-difluoronitrobenzene in tetrahydrofuran containing Raney nickel catalyst, in a Parr shaker, was treated with hydrogen at room temperature to give 2,5-difluoroaniline (2A).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04313755
Source datasetuspto-grants-1982_02
ORD IDord-94d33c196f004f1098815ff93a4b2e3c
Source noteuspto-grants-1982_02