反应详情

温度

80 °C

A mixture of 25.8 g of 2A, 18.5 g of formic acid and 100 ml of benzene was refluxed (80° C.) for 2 hours. The mixture was allowed to stand overnight. The solid that formed was separated and taken up in ether. Hexane was added. The solid that formed was separated and washed with cold hexane to give N-(2,5-difluorophenyl)formamide (2B), m.p.: 112°-114° C.

1. customThe solid that formed
2. customwas separated
3. additionHexane was added
4. customThe solid that formed
5. customwas separated
6. washwashed with cold hexane