Dichloromethane → 2,5-dioxopyrrolidin-1-yl 5-(2,4-difluorophenoxy)-1-isobutyl-1H-indazole-6-carboxylate
Reaction equation
[CH3:26][CH2:27][N:28]=[C:29]=[N:30][CH2:31][CH2:32][CH2:33][N:34]([CH3:35])[CH3:36].[Cl:45][CH2:46][Cl:47].[F:1][c:2]1[c:3]([O:4][c:5]2[cH:6][c:7]3[cH:8][n:9][n:10]([CH2:17][CH:18]([CH3:19])[CH3:20])[c:11]3[cH:12][c:13]2[C:14](=[O:15])[OH:16])[cH:21][cH:22][c:23]([F:25])[cH:24]1.[OH:37][N:38]1[C:39](=[O:44])[CH2:40][CH2:41][C:42]1=[O:43]>>[F:1][c:2]1[c:3]([O:4][c:5]2[cH:6][c:7]3[cH:8][n:9][n:10]([CH2:17][CH:18]([CH3:19])[CH3:20])[c:11]3[cH:12][c:13]2[C:14]([O:15][N:38]2[C:39](=[O:44])[CH2:40][CH2:41][C:42]2=[O:43])=[O:16])[cH:21][cH:22][c:23]([F:25])[cH:24]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-7a63c249202d40358cdd8ce6c4a1b6ce
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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