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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1446918Generated: October 31, 2026

1-Methylpiperazine → 3,6-Bis[2-(4-methylpiperazin-1-yl)ethoxy]acridine

https://huagongshe.com/reaction/1446918

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-MethylpiperazineHCID 53167—
Reactant3,6-Bis(2-chloroethoxy)acridine--hydrogen chloride (1/1)HCID 20184665—
Product3,6-Bis[2-(4-methylpiperazin-1-yl)ethoxy]acridineHCID 20553456—

Reaction Conditions

Temperature100 °C

Reaction Steps

The compound is prepared from 3,6-bis(2-chloroethoxy)acridine hydrochloride and N-methylpiperazine as described in Example 15, except that the mixture is heated at 100° C. for 24 hours to attain reaction and that the free base is isolated.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04314061
Source datasetuspto-grants-1982_02
ORD IDord-64be7bc7a21346ffae60dcf0ca51187b
Source noteuspto-grants-1982_02