HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic anhydride → HCID 178512621, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic anhydride | HCID 9845 | — |
| Reactant | 1-(4-(3-Aminophenyl)thiazol-2-yl)guanidine | HCID 178512611 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | HCID 178512621 | HCID 178512621 | — |
Reaction Steps
A mixture of 2-guanidino-4-(3-aminophenyl)-thiazole (1.2 g.) and trifluoroacetic anhydride (1.05 g.) was heated under reflux in acetonitrile for 3 hours. The mixture was cooled and the product (0.76 g.) filtered off to give 2-guanidino-4-(3-trifluoroacetylaminophenyl)thiazole trifluoroacetate, m.p. 152°-153° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04315009 |
| Source dataset | uspto-grants-1982_02 |
| ORD ID | ord-0777e3cd6a964f2bb96956c150017e99 |
| Source note | uspto-grants-1982_02 |