Chloroform → HCID 20552302, compound

Participants

Reaction Steps

31 parts by weight of thionyl chloride is dripped into 25 parts by weight of 1-[2-phenyl-2-hydroxyethyl]-1,2,4-triazole, 300 parts by weight of chloroform and 1 part by weight of dimethylformamide; the mixture is refluxed until no more gas evolves. After the mixture has been cooled and filtered, the residue is washed with a small amount of chloroform and recrystallized from isopropanol. There is obtained 22.5 parts by weight of 1-[2-phenyl-2-chloroethyl]-1,2,4-triazole hydrochloride; m.p.: 178° C.

Provenance & Evidence