Hydrochloric Acid → HCID 12832224, compound

HRID 1447064Notes

Reaction equation

HRID 1447064 reaction equation
C([NH:4][C:5]1[CH:6]=[C:7]([C:11]2[NH:12][C:13](=[O:19])[C:14](=[CH:17][CH:18]=2)[C:15]#N)[CH:8]=[CH:9][CH:10]=1)(=O)C.[OH-:20].[K+].Cl.[OH-:23].[Na+]>O>[NH2:4][C:5]1[CH:6]=[C:7]([C:11]2[NH:12][C:13](=[O:19])[C:14](=[CH:17][CH:18]=2)[C:15]([OH:23])=[O:20])[CH:8]=[CH:9][CH:10]=1

Participants

6

Reactant 4

HCID 313Hydrochloric AcidHCID 14797Potassium HydroxideHCID 14798Sodium HydroxideHCID 12918955HCID 12918955, compound

Product 1

HCID 12832224HCID 12832224, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

A mixture of 92.6 g (0.37 mol) of the above nitrile, 185 g of potassium hydroxide, and 740 ml of water is heated at 105° for 30 hrs. The cooled reaction mixture is poured into 285 ml of concentrated hydrochloric acid and ice. The pH of the suspension is adjusted to 5.0 with aqueous sodium hydroxide solution and the solid filtered, washed with water, and dried to give 81.2 g of the title compound. ##EQU2##

Workup

  1. temperatureis heated at 105° for 30 hrs
  2. customThe cooled reaction mixture
  3. filtrationthe solid filtered
  4. washwashed with water
  5. customdried

Sources & evidence

ORD record
ord-9fcd6ef8bdb84d0fa2af290409f9db1f
Source dataset
uspto-grants-1982_02
Patent number
US04315014

Reaction notes

Loading…