Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1,1'-Biphenyl, mixt. with 1,1'-oxybis(benzene) → Adrenosterone
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1,1'-Biphenyl, mixt. with 1,1'-oxybis(benzene) | HCID 24670 | — |
| 반응물 | 9alpha-Bromo-11beta-hydroxy-4-androstene-3,17-dione | HCID 11132685 | — |
| 생성물 | Adrenosterone | HCID 223997 | 80.6% |
반응 단계
Under argon gas, 1 g of 9α-bromo-11β-hydroxy-4-androstene-3,17-dione is agitated in 5 ml of "Dowtherm" A for 3 minutes at 250° C. To work up the reaction mixture, the solvent is removed by steam distillation, the residue is dried and recrystallized from methylene chloride-isopropyl ether, thus obtaining 635 mg of 4-androstene-3,11,17-trione, mp 214°-216° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04315866 |
| 출처 데이터셋 | uspto-grants-1982_02 |
| ORD ID | ord-2c3b4a462a634be3b27a2f6c4dd4d629 |
| 출처 메모 | uspto-grants-1982_02 |