HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → HCID 12895170, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | Epibromohydrin | HCID 18430 | — |
| Reactant | 1H-Indole-2-carboxylic acid, 4,5,6,7-tetrahydro-3-hydroxy-, ethyl ester | HCID 596121 | — |
| Solvent | Acetone | HCID 180 | — |
| Product | HCID 12895170 | HCID 12895170 | 100.1% |
Reaction Steps
Using the method described in Example V, 130 g of 3-hydroxy-4,5,6,7-tetrahydroindole-2-carboxylic acid ethyl ester, 170 g of epibromohydrin and 172 g of anhydrous potassium carbonate in 500 ml of acetone give 165 g of 1-(2-carboethoxy-4,5,6,7-tetrahydro-indol-3-oxy)-2,3-epoxypropane, of melting point 102°-104° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04315939 |
| Source dataset | uspto-grants-1982_02 |
| ORD ID | ord-be1b68054f5144a696c49986919436c7 |
| Source note | uspto-grants-1982_02 |