Ethanol → HCID 86736718, compound

HRID 1447584Notes

Reaction equation

HRID 1447584 reaction equation
[NH2:1][CH2:2][C:3]1[NH:4][C:5]([CH3:16])=[CH:6][CH:7]([C:9]2[CH:14]=[CH:13][CH:12]=[C:11]([Cl:15])[CH:10]=2)[CH:8]=1.[OH2:17].NN.[CH2:20]([OH:22])[CH3:21]>>[C:3]1(=[O:17])[N:1]([CH2:2][C:3]2[NH:4][C:5]([CH3:16])=[CH:6][CH:7]([C:9]3[CH:14]=[CH:13][CH:12]=[C:11]([Cl:15])[CH:10]=3)[CH:8]=2)[C:20](=[O:22])[C:21]2=[CH:16][CH:5]=[CH:6][CH:7]=[C:8]12

Participants

4

Reactant 3

HCID 702EthanolHCID 24654Hydrazine hydrate (1:1)HCID 86736719HCID 86736719, compound

Product 1

HCID 86736718HCID 86736718, compound

Procedure

2-Aminomethyl-6-methyl-4-(3'-chlorophenyl)-1,4-dihydropyridine -3-(carboxylic acid ethyl ester)-5-carboxylic acid methyl ester ##STR8## is obtained from 0.1 mol of 2-phthalimidomethyl-6-methyl-4-(3'-chlorophenyl)-1,4-dihydropyridine-3-(carboxylic acid ethyl ester)-5-carboxylic acid methyl ester and 22 ccs of hydrazine hydrate in 500 ccs of ethanol.

Sources & evidence

ORD record
ord-10e2d99778874f6bbd39121f149998e0
Source dataset
uspto-grants-1979_12
Patent number
US04177278

Reaction notes

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