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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1447588Generated: November 2, 2026

HCID 12608491, compound → N-{1-[2-(1H-Indol-3-yl)ethyl]piperidin-4-yl}urea

https://huagongshe.com/reaction/1447588

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 12608491HCID 12608491—
SolventSodium HydroxideHCID 14798—
ProductN-{1-[2-(1H-Indol-3-yl)ethyl]piperidin-4-yl}ureaHCID 12608470—

Reaction Steps

1-benzoyl-3-[1-(2-[3-indolyl]ethyl)piperid-4-yl]urea hydrochloride (1.180 g.) was refluxed in 2 N sodium hydroxide solution (20 ml) for 1 hour. The reaction mixture was cooled and the title compound was filtered off, (0.678 g., 86%) m.p. 212.2° (dec).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04177279
Source datasetuspto-grants-1979_12
ORD IDord-62dc37ddb1b84f608295df429d67b065
Source noteuspto-grants-1979_12