HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → HCID 12608569, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | HCID 12608504 | HCID 12608504 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 12608569 | HCID 12608569 | 96.7% |
Reaction Steps
1-Benzoyl-3-[1-(2-[3-indolyl]ethyl)piperid-4-yl]-thiourea (2.21 g) was refluxed in water (20 ml) containing sodium hydroxide (1.0 g) for 5 min. The mixture was cooled and filtered to afford the title compound (1.59 g). Crystallisation from EtOH-HCl/ether afforded the hydrochloride (1.467 g), m.p. 228°-9°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04177279 |
| Source dataset | uspto-grants-1979_12 |
| ORD ID | ord-76af09f6ac58493ab120296dda28fe5c |
| Source note | uspto-grants-1979_12 |