Hydrochloric Acid → HCID 20384409, compound

Participants

Reaction Conditions

Reaction Steps

22.6 g (0.08 mol) of ethyl N,N-diphenylcarbamoylacetate (m.p.=75°-76° C.) are added to a solution of 5.6 g(0.1 mol) of KOH in a mixture of 50 ml of water and 25 ml of ethanol. The mixture is heated to 40° C. with agitation until dissolution is complete (that is, for about 1 hour) and agitation is continued for two hours. Acidification is then carried out with 3 N HCl, followed by drying without heat, washing with water and drying.20.2 g (yield: 98%) of N,N-diphenylcarbamoylacetic acid (m.p.=126°-127° C.) are obtained.

Provenance & Evidence