HuagongsheHuagongshe Chemistry Print Report · For research reference only
Butylhydrazine → 6-phenyl-2-(2-hydroxyhexyl)-4-hydroxy-4,5-dihydropyridazine-3(2H)-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Butylhydrazine | HCID 77064 | — |
| Reactant | 1-Hydrazinylpropan-2-ol | HCID 236167 | — |
| Reactant | 2-Hydroxy-4-oxo-4-phenylbutanoic acid | HCID 516699 | — |
| Reactant | 2-Hydroxybutylhydrazine | HCID 4113127 | — |
| Reactant | 1-Hydrazino-2-hexanol | HCID 20384305 | — |
| Reactant | 3-Benzoyl-2-hydroxy-3-methyl-propionic acid | HCID 23243793 | — |
| Product | 6-phenyl-2-(2-hydroxyhexyl)-4-hydroxy-4,5-dihydropyridazine-3(2H)-one | HCID 20384303 | — |
Reaction Steps
When the above procedure is carried out using equivalent amounts of 3-benzoyl-2-hydroxy-propionic acid and 1-hydrazino-2-hexanol or 3-benzoyl-2-hydroxy-propionic acid and 1-hydrazino-2-propanol or 3-benzoyl-2-hydroxy-3-methyl-propionic acid and butyl hydrazine in place of the 3-benzoyl-2-hydroxy-propionic acid and 1-hydrazino-2-butanol used therein, there is obtained 6-phenyl-2-(2-hydroxyhexyl)-4-hydroxy-4,5-dihydropyridazine-3(2H)-one; 6-phenyl-2-(2-hydroxypropyl)-4-hydroxy-4,5-dihydropyridazin-3(2H)-one; or 2-butyl-4,5-dihydro-4-hydroxy-5-methyl-6-phenylpyridazin-3(2H)-one (m.p. 129°-155° C.), respectively.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04177273 |
| Source dataset | uspto-grants-1979_12 |
| ORD ID | ord-234728425da640fab80f509e2282d68d |
| Source note | uspto-grants-1979_12 |