2-Nitrophenol → HCID 20339195, compound

HRID 1447737Notes

Reaction equation

HRID 1447737 reaction equation
[N+:1]([C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=1[OH:10])([O-:3])=[O:2].[CH3:11][O:12][CH2:13][CH2:14]CBr.[C:17](=O)([O-])[O-].[K+].[K+]>CC(C)=O>[CH3:11][O:12][CH:13]([CH3:14])[CH2:17][O:10][C:5]1[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=1[N+:1]([O-:3])=[O:2]

Participants

5

Reactant 3

HCID 69472-NitrophenolHCID 11430Potassium CarbonateHCID 5245511-Bromo-3-methoxypropane

Product 1

HCID 20339195HCID 20339195, compound

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

2-Nitrophenol, 3-bromopropyl methyl ether, anhydrous potassium carbonate and acetone were reacted according to the procedure outlined in Example 1 to yield 2-methoxypropoxynitrobenzene, which was reduced to the corresponding aniline. The aniline was isolated by vacuum distillation.

Sources & evidence

ORD record
ord-7a66be49aee742f3a895df1bd995adb1
Source dataset
uspto-grants-1979_12
Patent number
US04178168

Reaction notes

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