Ethanol → HCID 20382544, compound

HRID 1447744Notes

Reaction equation

HRID 1447744 reaction equation
[SH:1][C:2]1[N:6]=[C:5]([C:7]2[CH:12]=[CH:11][C:10]([C:13]([CH3:16])([CH3:15])[CH3:14])=[CH:9][CH:8]=2)[NH:4][N:3]=1.Br[CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH3:29].C(O)C.[OH-].[Na+]>O>[CH2:29]([S:1][C:2]1[N:6]=[C:5]([C:7]2[CH:12]=[CH:11][C:10]([C:13]([CH3:16])([CH3:15])[CH3:14])=[CH:9][CH:8]=2)[NH:4][N:3]=1)[CH2:28][CH2:27][CH2:26][CH2:25][CH2:24][CH2:23][CH2:22][CH2:21][CH2:20][CH2:19][CH3:18]

Participants

6

Reactant 4

HCID 702EthanolHCID 89191-BromododecaneHCID 14798Sodium HydroxideHCID 178440780HCID 178440780, compound

Product 1

HCID 20382544HCID 20382544, compoundYield 59%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Conditions

Temperature
20 °C

Procedure

A mixture of 11.7 parts of 3-mercapto-5-(4-tert.-butylphenyl)-1,2,4-triazole, 12.5 parts of 1-bromododecane and 100 parts by volume of ethyl alcohol was heated at reflux temperature for four hours. After cooling to 20° C., a four percent weight/volume aqueous sodium hydroxide solution was added followed by 100 parts by volume of water. The precipitated product was filtered and dried yielding 59 percent of 3-(n-dodecylthio)-5-(4-tert.butylphenyl)-1,2,4-triazole which had a melting point of 87°-92° and the following elemental analysis:

Workup

  1. temperaturewas heated
  2. temperatureat reflux temperature for four hours
  3. filtrationThe precipitated product was filtered
  4. customdried

Sources & evidence

ORD record
ord-605006573fbb433cab6ddfb5b82d0795
Source dataset
uspto-grants-1979_12
Patent number
US04178253

Reaction notes

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