Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
L-Valine → m-Phenoxybenzyl 2-(5-methoxy-2-isoindolinyl)-3-methylbutanoate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | L-Valine | HCID 6287 | — |
| 반응물 | 1,2-Bis(bromomethyl)-3-trifluoromethylbenzene | HCID 20382846 | — |
| 반응물 | 2-(4-Trifluoromethyl-2-isoindolinyl)-3-methylbutanoic acid | HCID 20382857 | — |
| 반응물 | alpha-Cyano-m-phenoxybenzyl mesylate | HCID 20482835 | — |
| 생성물 | m-Phenoxybenzyl 2-(5-methoxy-2-isoindolinyl)-3-methylbutanoate | HCID 20382850 | — |
반응 단계
The α-cyano-m-phenoxybenzyl esters of the above are prepared using the procedure of Example 10 by reacting, e.g. 1,2-bis(bromomethyl)-3-trifluoromethylbenzene with valine to prepare 2-(4-trifluoromethyl-2-isoindolinyl)-3-methylbutanoic acid and esterifying using α-cyano-m-phenoxybenzyl mesylate.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04178293 |
| 출처 데이터셋 | uspto-grants-1979_12 |
| ORD ID | ord-cd888855f248413e852abb099127bdc7 |
| 출처 메모 | uspto-grants-1979_12 |