化工社化工社 化学情報印刷レポート · 研究参考用
Potassium Hydroxide → alpha-Cyano-m-phenoxybenzyl 2-(4,5,6,7-tetrachloro-2-isoindolinyl)-3-methylbutanoate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Potassium Hydroxide | HCID 14797 | — |
| 反応物 | m-Phenoxybenzyl 2-(4,5,6,7-tetrachloro-2-isoindolinyl)-3-methylbutanoate | HCID 20382845 | — |
| 反応物 | 2-(4,5,6,7-Tetrachloro-2-isoindolinyl)-3-methylbutanoic acid | HCID 20382847 | — |
| 反応物 | alpha-Cyano-m-phenoxybenzyl mesylate | HCID 20482835 | — |
| 溶媒 | Water ethanol | HCID 19096565 | — |
| 生成物 | alpha-Cyano-m-phenoxybenzyl 2-(4,5,6,7-tetrachloro-2-isoindolinyl)-3-methylbutanoate | HCID 53694847 | — |
反応手順
The ester, m-phenoxybenzyl 2-(4,5,6,7-tetrachloro-2-isoindolinyl)-3-methylbutanoate is hydrolyzed to 2-(4,5,6,7-tetrachloro-2-isoindolinyl)-3-methylbutanoic acid using KOH in ethanol/water, which is reacted with α-cyano-m-phenoxybenzyl mesylate to yield α-cyano-m-phenoxybenzyl 2-(4,5,6,7-tetrachloro-2-isoindolinyl)-3-methylbutanoate.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04178293 |
| 出典データセット | uspto-grants-1979_12 |
| ORD ID | ord-2a0a064a72df4b81aa703428209c2c45 |
| 出典メモ | uspto-grants-1979_12 |