18000-76-5 → HCID 70601729, compound

Participants

Reaction Steps

1.1 g. of 3β-methoxymethoxy-5-androsten-17-one is hydrogenated as disclosed in Example 25. The thus-obtained crude product is not quite uniform and contains, in addition to 3β-methoxymethoxy-5α-androstan-17-one, of which 0.65 g. can be obtained by crystallization from methanol, also proportions of 3β-methoxymethoxy-5α-androstan-17β-ol. By continuing the hydrogenation or by reduction with sodium borohydride, this product becomes the primary yield.

Provenance & Evidence