Methanethiol → HCID 54432291, compound

Participants

Reaction Steps

1.92 gm of methylmercaptan were added to an ice-cooled solution of 0.92 gm of sodium in 50 ml of ethanol. A suspension of 8.6 gm of 4,4-dimethyl-2-chloromethyl-2H,4H-isoquinoline-1,3-dione in 100 ml of ethanol was added, and the mixture was refluxed for 45 minutes. Thereafter, the reaction mixture was evaporated, the residue was triturated with water, filtered, the filter cake was recrystallized from isopropanol.

Provenance & Evidence