Dimethylamine → HCID 178486282, compound

HRID 1448046Notes

Reaction equation

CN.[CH3:3]NC.[Cl:6][C:7]1[CH:12]=[CH:11][C:10]([C:13]2[NH:14][C:15]([S:19](=[O:22])(=[O:21])[NH2:20])=[C:16](C)[N:17]=2)=[CH:9][CH:8]=1>>[Cl:6][C:7]1[CH:12]=[CH:11][C:10]([C:13]2[NH:17][CH:16]=[C:15]([S:19](=[O:22])(=[O:21])[NH:20][CH3:3])[N:14]=2)=[CH:9][CH:8]=1

Participants

Reactant 3

HCID 674Dimethylamine

HCID 6329Methylamine

HCID 178432509HCID 178432509, compound

Product 1

HCID 178486282HCID 178486282, compoundYield 4.4%

Procedure

Substituting aqueous methylamine for the dimethylamine in Example 3 2-(4-chlorophenyl)-4-methyl-sulfamoylimidazole, melting at 246°-248°, was obtained (4.4% yield).

Workup

customwas obtained (4.4% yield)

Sources & evidence

ORD record: ord-6683a8b947014ba29c64ea87c930f000
Source dataset: uspto-grants-1979_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04179512

Reaction notes

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