Hydroxyamine hydrochloride → HCID 73677389, compound

HRID 1448061Notes

Reaction equation

HRID 1448061 reaction equation
[O:1]1[C:7]2[CH:8]=[CH:9][CH:10]=[CH:11][C:6]=2[CH:5]=[CH:4][CH:3]=[CH:2]1.[ClH:12].[NH2:13][OH:14]>N1C=CC=CC=1>[Cl:12][C:10]1[CH:9]=[CH:8][C:7]2[O:1][CH2:2][CH2:3][CH2:4][C:5](=[N:13][OH:14])[C:6]=2[CH:11]=1

Participants

4

Reactant 2

HCID 443297Hydroxyamine hydrochlorideHCID 12254036HCID 12254036, compound

Product 1

HCID 73677389HCID 73677389, compound

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent2×

Procedure

A solution of 50 g of the benzoxepine previously obtained and 26 g of hydroxylamine hydrochloride in 200 ml of pyridine is kept at the reflux temperature of pyridine for 51/2 hours.

Workup

  1. custom2 hours

Sources & evidence

ORD record
ord-1767193ca67b41b1a7fbcced2dab7c0f
Source dataset
uspto-grants-1979_12
Patent number
US04179516

Reaction notes

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