HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 135737565, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Methyl iodide | HCID 6328 | — |
| Reactant | HCID 135737578 | HCID 135737578 | — |
| Solvent | Methanol | HCID 887 | — |
| Solvent | Sodium | HCID 5360545 | — |
| Product | HCID 135737565 | HCID 135737565 | — |
Reaction Steps
To 4.2 g of 10-hydroxy-2-(hydroxymethyl)pyrazolo[1,5-c]quinazoline-5(6H)-one in a solution of 0.58 g sodium dissolved in 100 ml dry methanol is added 2.9 g of methyl iodide. After stirring for 3 hours at 50°, the reaction is neutralized with one equivalent of 1 N hydrochloric acid, evaporated and the residue recrystallized from absolute ethanol to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04179561 |
| Source dataset | uspto-grants-1979_12 |
| ORD ID | ord-39d133a773d741cd984c0d4d35e3d02c |
| Source note | uspto-grants-1979_12 |