反应详情

温度

0 °C

3-Bromo-7-hydroxy-2-isopropyl-chromen-4-one (778 mg, 2.75 mmol) is dissolved in concentrated sulphuric acid (4 ml), and the solution is cooled to 0° C. A solution of fuming nitric acid (189 mg, 3 mmol) in concentrated sulphuric acid (1 ml) is added dropwise. The mixture is stirred at 0° C. for 30 min, poured onto ice, recovered by filtration and dried to give a cream-coloured solid.

1. additionpoured onto ice
2. filtrationrecovered by filtration
3. customdried
4. customto give a cream-coloured solid