Hydrochloric Acid → HCID 86736750, compound

HRID 1448580Notes

Reaction equation

HRID 1448580 reaction equation
[Cl:1][C:2]1[S:6][C:5]([S:7]([OH:10])(=[O:9])=[O:8])=[C:4]([C:11]([O-:13])=[O:12])[CH:3]=1.[Na+].[OH-].[K+:16].Cl>O>[Cl:1][C:2]1[S:6][C:5]([S:7]([OH:10])(=[O:9])=[O:8])=[C:4]([C:11]([O-:13])=[O:12])[CH:3]=1.[K+:16]

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 14797Potassium HydroxideHCID 86736749HCID 86736749, compound

Product 1

HCID 86736750HCID 86736750, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

129 g. of sodium 5-chloro-2-sulfothiophene-3-carboxylate are dissolved hot in a solution of 84.7 g. of caustic potash in 430 ml. of water, acidified with 130 ml. of concentrated HCl to a pH of 1, and slowly cooled to 5°. The precipitate that separates out is suction filtered without rewashing. The filtrate is concentrated by evaporation to 220 ml. and again cooled to 5°. The precipitate that separates out is suction filtered, combined with the previously obtained product, and dried in vacuo at 110°. Potassium 5-chloro-2-sulfothiophene-3-carboxylate is obtained.

Workup

  1. filtrationThe precipitate that separates out is suction filtered without rewashing
  2. concentrationThe filtrate is concentrated by evaporation to 220 ml
  3. temperatureand again cooled to 5°
  4. filtrationThe precipitate that separates out is suction filtered
  5. customdried in vacuo at 110°

Sources & evidence

ORD record
ord-680ee32b93034ab88b9529a9559be8a5
Source dataset
uspto-grants-1979_12
Patent number
US04180662

Reaction notes

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