HCID 20380286, compound → HCID 20380313, compound

HRID 1448598Notes

Reaction equation

HRID 1448598 reaction equation
[ClH:1].C([N:9]1[CH2:14][CH:13]=[C:12]([C:15]2[C:20]([O:21][CH3:22])=[CH:19][C:18]([CH:23]([CH3:31])[CH:24]([CH3:30])[CH2:25][CH2:26][CH2:27][CH2:28][CH3:29])=[CH:17][C:16]=2[OH:32])[CH2:11][CH2:10]1)C1C=CC=CC=1>COCCO.[Pd]>[ClH:1].[NH:9]1[CH:10]=[CH:11][CH:12]([C:15]2[C:20]([O:21][CH3:22])=[CH:19][C:18]([CH:23]([CH3:31])[CH:24]([CH3:30])[CH2:25][CH2:26][CH2:27][CH2:28][CH3:29])=[CH:17][C:16]=2[OH:32])[CH2:13][CH2:14]1

Participants

4

Reactant 1

HCID 20380286HCID 20380286, compound

Product 1

HCID 20380313HCID 20380313, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 80192-MethoxyethanolSolvent

Procedure

The compound of Example XXVII (8.0 g) in 2-methoxyethanol was hydrogenated using 5% Pd on carbon as a catalyst and stopping the reaction after one equivalent was taken up. The product (5.3 g) had an m.p. of 192°-194° (83%).

Workup

  1. customthe reaction after one equivalent

Sources & evidence

ORD record
ord-b4738f695dd449fabc0080ba4a7a0cb8
Source dataset
uspto-grants-1979_12
Patent number
US04180669

Reaction notes

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