1-Chloro-4-nitrobenzene → 4-Nitrodiphenylamine

Participants

Reaction Steps

Into a suitable reactor is charged 64.4 parts by weight (0.45 mole) of sodium formanilide and 8.0 parts by weight (0.05 mole) of potassium formanilide to give a 90/10 ratio of the salts. In addition, there is added 23.4 parts by weight (0.193 mole) of formanilide and 60.6 parts by weight (0.385) of p-nitrochlorobenzene. The mixture is heated and stirred for 1.5 hours at 152°-160° C. The product is isolated as described in Example 1 to obtain 75.1 parts by weight or 93% yield of 4-nitrodiphenylamine. Conversion of p-nitrochlorobenzene is 98.4%.

Provenance & Evidence