HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(3-hydroxy-1-phenyl-1H-indol-2-yl)-2-(methylsulfonyl)ethanone → 3-Hydroxy-1-phenyl-1H-indol-2-yl methyl ketone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(3-hydroxy-1-phenyl-1H-indol-2-yl)-2-(methylsulfonyl)ethanone | HCID 12511319 | — |
| Reactant | Acetic acid ethanol | HCID 18476134 | — |
| Solvent | Water | HCID 962 | — |
| Product | 3-Hydroxy-1-phenyl-1H-indol-2-yl methyl ketone | HCID 12511321 | — |
Reaction Steps
In a manner analogous to that of Example 5, the title compound was prepared from 1-(3-hydroxy-1-phenyl-1H-indol-2-yl)-2-(methylsulfonyl)ethanone. The product was obtained as green needles of mpt. 127°-130° from the condensed ethanol-acetic acid filtrate by the addition of warm water, followed by slow cooling.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04188326 |
| Source dataset | uspto-grants-1980_02 |
| ORD ID | ord-ff8ecc3676cd48da8a8ddebc90ae7b87 |
| Source note | uspto-grants-1980_02 |