Water → HCID 13405244, compound

Participants

Reaction Steps

8-Methoxy-1,4-benzodioxan-2-carboxamide (2.41 g.) in 50% hydrochloric acid (35 ml.) was stirred at 100° C. for 1 hour. The resulting solution was cooled, diluted with water (200 ml.), extracted with chloroform (3×100 ml.) then the extracts dried (MgSO4) and evaporated in vacuo. The solid residue (1.8 g.) was recrystallized from water (m.p. 75°-78° C.) then from ethyl acetate/hexane to give 8-methoxy-1,4-benzodioxan-2-carboxylic acid, m.p. 131°-132° C.

Provenance & Evidence