HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Bromotoluene → 1-Benzyl-4-(4-methylphenyl)piperidin-4-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Bromotoluene | HCID 7805 | — |
| Reactant | 1-Benzyl-4-piperidone | HCID 19220 | — |
| Product | 1-Benzyl-4-(4-methylphenyl)piperidin-4-ol | HCID 198608 | — |
Reaction Steps
The starting material can be produced in the following manner: In a manner analogous to that described in Example 6, 100 g of p-bromotoluene and 110 g of N-benzyl-4-piperidone are reacted to give N-benzyl-4-hydroxy-4-(4-methylphenyl)-piperidine, b.p.0.05 =185°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04188396 |
| Source dataset | uspto-grants-1980_02 |
| ORD ID | ord-3d70023131c940438004525c06852faf |
| Source note | uspto-grants-1980_02 |