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HRID1449011

反应详情

EQUATION

反应方程式

HRID 1449011 的结构方程式

REACTANTS

反应物

4
结构：CCO
HCID702

Ethanol

C2H6O

结构：O=Cc1cccnc1
HCID10371

3-Pyridinecarboxaldehyde

C6H5NO

结构：CCOC(=O)/C=C(/C)N
HCID643756

未命名化合物

结构：CCOC(=O)CC(=O)CN1C(=O)c2ccccc2C1=O
HCID701239

Ethyl 4-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-3-oxobutanoate

C14H13NO5

PRODUCTS

生成物

1
结构：CCOC(=O)C1=C(C)NC(CN2C(=O)c3ccccc3C2=O)=C(C(=O)OCC)C1c1ccccn1
HCID70590121

未命名化合物

收率 65%

PROCEDURE

实验过程

A solution of 4.7 ccs of pyridine-3-aldehyde, 12.4 g of phthalimidoacetoacetic acid ethyl ester and 5.85 g of β-aminocrotonic acid ethyl ester in 100 ccs of ethanol is heated under reflux for 24 hours and, after cooling and filtering, crystals (beige) of melting point 165° C. are obtained, yield: 65%.

WORKUP

后处理

  1. temperatureunder reflux for 24 hours
  2. temperatureafter cooling
  3. filtrationfiltering
  4. customcrystals (beige) of melting point 165° C. are obtained