Ethylamine → HCID 20350133, compound

HRID 1449142Notes

Reaction equation

HRID 1449142 reaction equation
Cl[C:2]1[N:10]=[CH:9][N:8]=[C:7]2[C:3]=1[N:4]=[CH:5][N:6]2[CH2:11][C:12]1[C:17]([Cl:18])=[CH:16][CH:15]=[CH:14][C:13]=1[Cl:19].[CH2:20]([NH2:22])[CH3:21]>CO>[Cl:19][C:13]1[CH:14]=[CH:15][CH:16]=[C:17]([Cl:18])[C:12]=1[CH2:11][N:6]1[CH:5]=[N:4][C:3]2[C:7]1=[N:8][CH:9]=[N:10][C:2]=2[NH:22][CH2:20][CH3:21]

Participants

4

Reactant 2

HCID 6341EthylamineHCID 14416083HCID 14416083, compound

Product 1

HCID 20350133HCID 20350133, compoundYield 79%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

6-Chloro-9-(2,6-dichlorobenzyl)purine (314 mg), 322 mg of 70% aqueous ethylamine and 25 ml of methanol were treated in the same manner as Example 2, whereby 255 mg (yield 79%) of 9-(2,6-dichlorobenzyl)-6-ethylaminopurine was obtained as needles melting at 222°-223° C.

Sources & evidence

ORD record
ord-3e6954e56acc44758f472f0fe7697924
Source dataset
uspto-grants-1980_02
Patent number
US04189485

Reaction notes

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