Allylamine → HCID 20350127, compound

HRID 1449145Notes

Reaction equation

HRID 1449145 reaction equation
Cl[C:2]1[N:10]=[CH:9][N:8]=[C:7]2[C:3]=1[N:4]=[CH:5][N:6]2[CH2:11][C:12]1[C:17]([Cl:18])=[CH:16][CH:15]=[CH:14][C:13]=1[Cl:19].[CH2:20]([NH2:23])[CH:21]=[CH2:22]>CO>[CH2:20]([NH:23][C:2]1[N:10]=[CH:9][N:8]=[C:7]2[C:3]=1[N:4]=[CH:5][N:6]2[CH2:11][C:12]1[C:17]([Cl:18])=[CH:16][CH:15]=[CH:14][C:13]=1[Cl:19])[CH:21]=[CH2:22]

Participants

4

Reactant 2

HCID 7853AllylamineHCID 14416083HCID 14416083, compound

Product 1

HCID 20350127HCID 20350127, compoundYield 81%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

6-Chloro-9-(2,6-dichlorobenzyl)purine (314 mg), 286 mg of allylamine and 25 ml of methanol were treated in the same manner as Example 2, whereby 271 mg (yield 81%) of 6-allylamino-9-(2,6-dichlorobenzyl)purine was obtained as colorless prisms melting at 202.5°-204° C.

Sources & evidence

ORD record
ord-1c12319955f644c79c39e69a5474daa7
Source dataset
uspto-grants-1980_02
Patent number
US04189485

Reaction notes

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