2-Chloro-6,7-dimethoxy-4-quinazolinamine → HCID 53673885, compound

Participants

Reaction Steps

A mixture of 479 mg. of 2-chloro-4-amino-6,7-dimethoxyquinazoline and 461 mg. of 2-methylcinnamoylpiperazine in 10 ml. of isoamyl alcohol was heated under reflux for 4 hours. After ice-cooling, the reaction mixture was filtered and the product thus obtained was washed with ethanol to yield 812 mg. of the desired product as the hydrochloride.

Provenance & Evidence