Hydrochloric Acid → HCID 20349347, compound

HRID 1449377Notes

Reaction equation

HRID 1449377 reaction equation
[C:1]([C:6]1[C:15](=[O:16])[C:14]2[C:9]([C:10]3[C:11]([N:17]=[N:18][CH:19]=3)=[CH:12][CH:13]=2)=[N:8][CH:7]=1)([O:3]CC)=[O:2].Cl>[OH-].[Na+]>[C:1]([C:6]1[C:15](=[O:16])[C:14]2[C:9]([C:10]3[C:11]([N:17]=[N:18][CH:19]=3)=[CH:12][CH:13]=2)=[N:8][CH:7]=1)([OH:3])=[O:2]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 20349349HCID 20349349, compound

Product 1

HCID 20349347HCID 20349347, compound

Reagents, catalysts & solvents 1

HCID 14798Sodium HydroxideSolvent

Procedure

3-Carbethoxy-4-oxo-pyrazolo[5,4-h]quinoline (0.05 mole) is added to a 10% sodium hydroxide solution (200 ml). The reaction mixture is refluxed for 3 hours, which time is required for complete dissolution to occur. The cold solution is made acidic with a dilute hydrochloric acid solution. The resulting 3-carboxy-4-oxo-pyrazolo[5,4-h]quinoline precipitates out. It is suction filtered, washed with water and dried in vacuo.

Workup

  1. temperatureThe reaction mixture is refluxed for 3 hours
  2. dissolutionwhich time is required for complete dissolution
  3. customThe resulting 3-carboxy-4-oxo-pyrazolo[5,4-h]quinoline precipitates out
  4. filtrationfiltered
  5. washwashed with water
  6. customdried in vacuo

Sources & evidence

ORD record
ord-2e90d17002ea4318803bb02fb526b38f
Source dataset
uspto-grants-1980_02
Patent number
US04190661

Reaction notes

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