HCID 19978307, compound → HCID 19978304, compound

Participants

Reaction Conditions

Reaction Steps

The compound (1.0 g, 1.9 mmoles) obtained in the above described paragraph (b) was dissolved in the mixed solution of 3 ml of dioxane and 3 ml of concentrated aqueous ammonia, and the resulting solution was heated in a sealed tube at 120° C. for 24 hours. The reaction was concentrated under reduced pressure, and the residue was then purified by chromatography on a silica gel column to give 0.56 g of the title compound.

Provenance & Evidence