Hydrogen Peroxide → HCID 15335357, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of 2-(trifluoromethyl -3-[(trifluoromethyl)thio]indole (0.96 g, 3.36 mmole) and 30% hydrogen peroxide (1.15 mL, 10.1 mmole) in acetic acid is heated at 50° C. for 16 hours, cooled to room temperature, poured onto water and filtered. The filter cake is air-dried to give the title product as a colorless solid, 0.535 g (50% yield), mp 183°-185° C., identified by IR, 1HNMR, 13CNMR, 19FNMR and mass spectral analyses.

Provenance & Evidence