HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Benzyl-4-[3-(1,1-dimethylethylamino)pyridyl]piperazine → 1-[3-(1,1-Dimethylethylamino)pyridyl]piperazine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Benzyl-4-[3-(1,1-dimethylethylamino)pyridyl]piperazine | HCID 21477623 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 1-[3-(1,1-Dimethylethylamino)pyridyl]piperazine | HCID 11042683 | — |
Reaction Steps
1- Benzyl-4-[3-(1,1-dimethylethylamino)pyridyl]piperazine (PREPARATION 96, 4.25 g, 13.10 mmol) is dissolved in 100 ml ethanol. Palladium (10% on carbon, 1.0 g) is added and the solution hydrogenated at 40 psi hydrogen gas. The mixture is filtered and concentrated to give the title compound, NMR (300 MHz, CD3OD) 7.53, 7.19, 6.93, 2.95, 1.39 δ.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05599930 |
| Source dataset | uspto-grants-1997_02 |
| ORD ID | ord-f87236048290426e8144f2d1fdb4d147 |
| Source note | uspto-grants-1997_02 |