Tetrahydrofuran → 1-(2-(Trifluoromethyl)phenyl)cyclopentanol
Reaction equation
[Br:1][c:2]1[c:3]([C:8]([F:9])([F:10])[F:11])[cH:4][cH:5][cH:6][cH:7]1.[CH2:23]1[O:24][CH2:25][CH2:26][CH2:27]1.[CH3:12][CH2:13][CH2:14][CH2:15][Li:16].[O:17]=[C:18]1[CH2:19][CH2:20][CH2:21][CH2:22]1>>[c:2]1([C:18]2([OH:17])[CH2:19][CH2:20][CH2:21][CH2:22]2)[c:3]([C:8]([F:9])([F:10])[F:11])[cH:4][cH:5][cH:6][cH:7]1Participants
5
Sources & evidence
- ORD record
- ord-8782df11dffb4741a142916262daa03a
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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