Benzoic Acid → HCID 86750282, compound

HRID 1449814Notes

Reaction equation

HRID 1449814 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[CH:8]([OH:18])[CH2:9][NH:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][OH:17].[C:19](O)(=[O:26])[C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1.C([O:30][C:31](=[O:33])C)C.[CH3:34][OH:35]>>[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[CH:8]([OH:18])[CH2:9][NH:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][O:17][C:19](=[O:26])[C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1.[C:31]([O-:30])(=[O:33])[C:34]([O-:17])=[O:35]

Participants

4

Reactant 3

HCID 243Benzoic AcidHCID 21584119Ethylacetate methanolHCID 23352640HCID 23352640, compound

Product 1

HCID 86750282HCID 86750282, compound

Procedure

According to method II from 1-(2-chlorophenyl)-2-(6-hydroxy-1-hexylamino)ethanol and benzoic acid. Working up by means of chromatography (ethyl-acetate/methanol 1:1). Recrystallized as the oxalate from acetone. Melting point: 144°-148° C.

Workup

  1. customRecrystallized as the oxalate from acetone

Sources & evidence

ORD record
ord-1696aaf8879b4648ad0a50298f25ebcc
Source dataset
uspto-grants-1997_02
Patent number
US05599966

Reaction notes

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