Phenylacetic Acid → HCID 86750285, compound

HRID 1449816Notes

Reaction equation

HRID 1449816 reaction equation
[OH:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][NH:8][CH2:9][CH:10]([C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1)[OH:11].[C:18]1(C[C:25]([OH:27])=[O:26])[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1.[C:28]([O:31]CC)(=[O:30])[CH3:29].[CH3:34][OH:35]>>[C:28]([O:31][C:18]1[CH:19]=[CH:20][CH:21]=[CH:22][C:23]=1[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][NH:8][CH2:9][CH:10]([OH:11])[C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1)(=[O:30])[CH3:29].[C:25]([O-:27])(=[O:26])[C:34]([O-:1])=[O:35]

Participants

4

Reactant 3

HCID 999Phenylacetic AcidHCID 21584119Ethylacetate methanolHCID 54456417HCID 54456417, compound

Product 1

HCID 86750285HCID 86750285, compound

Procedure

According to method II from 2-(6-hydroxy-1-hexylamino)-1-phenylethanol and phenylacetic acid. Working up by means of chromatography (ethyl acetate/methanol 1:1). Recrystallized as the oxalate from acetone. Melting point: 116°-121° C.

Workup

  1. customRecrystallized as the oxalate from acetone

Sources & evidence

ORD record
ord-ed2f5ae574dc466e8cfa64ccee02ce37
Source dataset
uspto-grants-1997_02
Patent number
US05599966

Reaction notes

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