HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dibenzylamine → 4-t-Butoxy-6-dibenzylamino-2,5-difluoro-3-methylpyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dibenzylamine | HCID 7656 | — |
| Reactant | 4-(tert-Butoxy)-2,3,6-trifluoro-5-methylpyridine | HCID 10751339 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 4-t-Butoxy-6-dibenzylamino-2,5-difluoro-3-methylpyridine | HCID 19691352 | — |
Reaction Steps
4-t-Butoxy-2,5,6-trifluoro-3-methylpyridine from Step 253c above is reacted with dibenzylamine in ethanol at reflux temperature. Solvent is removed, and the residue is dissolved in methylene chloride and washed with water. The product is purified by column chromatography.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05599816 |
| Source dataset | uspto-grants-1997_02 |
| ORD ID | ord-54f483c7e7044eaf81402fcac4a6d42e |
| Source note | uspto-grants-1997_02 |