4-(Chloromethyl)-2,5-oxazolidinedione → HCID 86750326, compound

HRID 1450294Notes

Reaction equation

HRID 1450294 reaction equation
[NH2:1][CH2:2][CH:3]1[O:7][CH2:6][CH:5]([S:8][C:9]2[CH:15]([CH3:16])[CH:14]3[N:11]([C:12](=[O:20])[CH:13]3[CH:17]([OH:19])[CH3:18])[C:10]=2[C:21]([OH:23])=[O:22])[CH2:4]1.[Cl:24][CH2:25][CH:26]1[C:30](=O)[O:29]C(=O)[NH:27]1>P([O-])([O-])([O-])=O.[Na+].[Na+].[Na+]>[NH2:27][CH:26]([CH2:25][Cl:24])[C:30]([NH:1][CH2:2][CH:3]1[O:7][CH2:6][CH:5]([S:8][C:9]2[CH:15]([CH3:16])[CH:14]3[N:11]([C:12](=[O:20])[CH:13]3[CH:17]([OH:19])[CH3:18])[C:10]=2[C:21]([OH:23])=[O:22])[CH2:4]1)=[O:29]

Participants

4

Reactant 2

HCID 217642954-(Chloromethyl)-2,5-oxazolidinedioneHCID 749715283-[[5-(Aminomethyl)tetrahydro-3-furanyl]thio]-6-(1-hydroxyethyl)-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid

Product 1

HCID 86750326HCID 86750326, compoundYield 38.7%

Reagents, catalysts & solvents 1

HCID 24243Trisodium PhosphateSolvent

Procedure

The title compound is prepared by the procedure of Example 47 using 0.0685 g of product from Example 46 in 1.5 ml of sodium phosphate buffer (pH 8.5) and 0.0299 g of product from Example 53 to give 0.0347 g of the desired product.

Sources & evidence

ORD record
ord-3ddff18cfca94032ae56e4bdf65b5dc7
Source dataset
uspto-grants-1997_02
Patent number
US05602118

Reaction notes

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