反应详情

A mixture of 0.80 g of product from Example 57, 0.431 g of sodium iodide and 20 ml of acetone is heated at reflux temperature for 5 days. The reaction is concentrated in vacuo and the residue purified by chromatography (silica Gel: 80% ethyl acetate/hexane) to give 0.472 g of the desired product.

1. temperatureis heated
2. temperatureat reflux temperature for 5 days
3. concentrationThe reaction is concentrated in vacuo
4. customthe residue purified by chromatography (silica Gel: 80% ethyl acetate/hexane)