Dimethylformamide → HCID 9837462, compound

HRID 1450633Notes

Reaction equation

HRID 1450633 reaction equation
O[C:2]1[S:3][C:4](I)=[CH:5][C:6]=1C.CN(C)[CH:11]=[O:12]>>[OH:12][CH2:11][C:2]1[S:3][C:4]([C:4]2[S:3][C:2]([CH2:11][OH:12])=[CH:6][CH:5]=2)=[CH:5][CH:6]=1

Participants

3

Reactant 2

HCID 6228DimethylformamideHCID 18920440HCID 18920440, compound

Product 1

HCID 9837462HCID 9837462, compound

Procedure

5,5'-Dihydroxymethyl-2,2'-bithiophene was also obtained by refluxing 2-hydroxy-methyl-5-iodo-thiophene with Cu powder in dimethyl formamide. The Ullmann condensation yielded a very poor amount of 5,5'-dihydroxymethyl-2,2'-bithiophene.

Workup

  1. customThe Ullmann condensation

Sources & evidence

ORD record
ord-3109e9596ab04ba3a73ea958e7dfe3fa
Source dataset
uspto-grants-1997_02
Patent number
US05602170

Reaction notes

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