Stannous Chloride → HCID 19358852, compound

HRID 1451055Notes

Reaction equation

HRID 1451055 reaction equation
Cl[C:2]1[C:7]([N+:8]([O-])=O)=[C:6]([CH3:11])[N:5]=[C:4]([S:12][CH3:13])[N:3]=1.[CH2:14]([C:16]1[NH:17][CH:18]=[C:19]([CH3:21])[N:20]=1)[CH3:15].[Sn](Cl)Cl.[C:25](N1C=CN=C1)(N1C=CN=C1)=[O:26]>>[CH2:14]([C:16]1[N:17]2[C:18]([C:25](=[O:26])[NH:8][C:7]3[C:6]([CH3:11])=[N:5][C:4]([S:12][CH3:13])=[N:3][C:2]=32)=[C:19]([CH3:21])[N:20]=1)[CH3:15]

Participants

5

Reactant 4

HCID 24479Stannous ChlorideHCID 682631,1'-CarbonyldiimidazoleHCID 19358860HCID 19358860, compoundHCID 178437635HCID 178437635, compound

Product 1

HCID 19358852HCID 19358852, compound

Procedure

Prepared by treatment of 4-chloro-6-methyl-2-(methylthio)-5-nitropyrimidine with 2-ethyl-4-methylimidazole, reduction with tin (II) chloride, and cyclization with carbonyldiimidazole.

Sources & evidence

ORD record
ord-ff2c92fa70b245b3b6d45f59b85327a1
Source dataset
uspto-grants-1997_02
Patent number
US05602252

Reaction notes

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