Sodium Hydroxide → HCID 86750370, compound

Participants

Reaction Steps

A mixture of methyl 4-acetylamino-3-[(hydroxylimino)methyl]benzoate (142 mg, 0.6 mmol) and 1N sodium hydroxide (1.0 mL, 1.0 mmol) was stirred at room temperature for 4 h. The mixture was filtered through a pad of cotton and neutralized with dil. hydrochloric acid. The precipitate obtained was collected by filtration, washed with water, and dried under vacuum over acetone for 24 h to give 95 mg (71%) of the title compound as a white powder, mp 215°-218° C. (dec).

Provenance & Evidence