Cuminaldehyde → HCID 4504628, compound

HRID 1451143Notes

Reaction equation

HRID 1451143 reaction equation
[N+:1]([C:4]1[CH:9]=[CH:8][C:7]([NH:10][NH2:11])=[CH:6][CH:5]=1)([O-:3])=[O:2].[CH:12]([C:15]1[CH:22]=[CH:21][C:18]([CH:19]=O)=[CH:17][CH:16]=1)([CH3:14])[CH3:13]>CO>[N+:1]([C:4]1[CH:5]=[CH:6][C:7]([NH:10][N:11]=[CH:19][C:18]2[CH:21]=[CH:22][C:15]([CH:12]([CH3:14])[CH3:13])=[CH:16][CH:17]=2)=[CH:8][CH:9]=1)([O-:3])=[O:2]

Participants

4

Reactant 2

HCID 326CuminaldehydeHCID 3310889(4-Nitrophenyl)hydrazine

Product 1

HCID 4504628HCID 4504628, compoundYield 92.1%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Conditions

Temperature
100 °C

Procedure

In 20 ml of methanol was dissolved 3.06 g of 4-nitrophenylhydrazine. With 2.96 g of 4-isopropylbenzaldehyde added, the solution was refluxed at 100° C. for one hour. With the progress of reaction, crystals gradually precipitated. The crystals were collected by suction filtration, washed with methanol, and dried at 80° C. for 2 hours, obtaining 5.21 g (yield 92%) of pale yellow crystals.

Workup

  1. customWith the progress of reaction, crystals
  2. customgradually precipitated
  3. filtrationThe crystals were collected by suction filtration
  4. washwashed with methanol
  5. customdried at 80° C. for 2 hours

Sources & evidence

ORD record
ord-444292973dab40c89b31814cae0b4b8f
Source dataset
uspto-grants-1997_02
Patent number
US05604004

Reaction notes

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